Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.33 |
| ▸ | HTR3B | O95264 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399179 | 1.00 | ITGA4 (0.36) | ITGA4ITGB7BCHESLC6A3LMNA | |
| SCHEMBL9491327 | 0.89 | CNR2 (0.41) | ITGA4ITGB7LMNACYP2D6 | |
| SCHEMBL9490368 | 0.89 | CNR2 (0.41) | ITGA4ITGB7LMNACYP2D6 | |
| SCHEMBL9490471 | 0.89 | CNR2 (0.41) | ITGA4ITGB7LMNACYP2D6 | |
| SCHEMBL9520161 | 0.89 | CNR2 (0.41) | ITGA4ITGB7LMNACYP2D6 | |
| SCHEMBL9490420 | 0.87 | CYP2D6 (0.36) | ITGA4ITGB7LMNAMAPTCYP2D6 | |
| SCHEMBL9521837 | 0.87 | CYP2D6 (0.36) | ITGA4ITGB7LMNAMAPTCYP2D6 | |
| SCHEMBL9521077 | 0.84 | ALDH1A1 (0.41) | ITGA4ITGB7LMNANPSR1MAPT | |
| SCHEMBL9490387 | 0.84 | ALDH1A1 (0.41) | ITGA4ITGB7LMNANPSR1MAPT | |
| SCHEMBL9491487 | 0.82 | ITGA4 (0.41) | ITGA4ITGB7BCHESLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342848-A | Relaxation of vascular smooth muscle | RHONE-POULENC RORER LIMITED (GB) | 1994-08-30 | — | — | US | claimed |
| WO-1991012242-A1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1991-08-22 | — | — | WO | claimed |
| US-5342848-A | Relaxation of vascular smooth muscle | RHONE-POULENC RORER LIMITED (GB) | 1994-08-30 | — | — | US | disclosed |
| EP-0514419-A1 | THIOFORMAMIDE DERIVATIVES | Aventis Pharma S.A. (FR) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991012242-A1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1991-08-22 | — | — | WO | disclosed |