Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490420 | 1.00 | CYP2D6 (0.36) | CYP2D6HPGDMAPTALDH1A1ITGA4 | |
| SCHEMBL9520161 | 0.94 | CNR2 (0.41) | CYP2D6HPGDALDH1A1ITGA4ITGB7 | |
| SCHEMBL9491327 | 0.94 | CNR2 (0.41) | CYP2D6HPGDALDH1A1ITGA4ITGB7 | |
| SCHEMBL9490471 | 0.94 | CNR2 (0.41) | CYP2D6HPGDALDH1A1ITGA4ITGB7 | |
| SCHEMBL9490368 | 0.94 | CNR2 (0.41) | CYP2D6HPGDALDH1A1ITGA4ITGB7 | |
| SCHEMBL9490387 | 0.93 | ALDH1A1 (0.41) | MAPTALDH1A1ITGA4ITGB7CNR2 | |
| SCHEMBL9521077 | 0.93 | ALDH1A1 (0.41) | MAPTALDH1A1ITGA4ITGB7CNR2 | |
| SCHEMBL9521441 | 0.92 | CYP2D6 (0.36) | CYP2D6HPGDALDH1A1ITGA4ITGB7 | |
| SCHEMBL9491119 | 0.92 | CYP2D6 (0.36) | CYP2D6HPGDALDH1A1ITGA4ITGB7 | |
| SCHEMBL9490797 | 0.92 | ALDH1A1 (0.39) | CYP2D6HPGDALDH1A1P2RX7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |
| EP-0390693-A1 | Thioformamide derivatives | RHONE-POULENC SANTE (FR) | 1990-10-03 | — | — | EP | disclosed |