Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490368 | 1.00 | CNR2 (0.41) | CNR2ITGA4ITGB7VNN1ALDH1A1 | |
| SCHEMBL9491327 | 1.00 | CNR2 (0.41) | CNR2ITGA4ITGB7VNN1ALDH1A1 | |
| SCHEMBL9490471 | 1.00 | CNR2 (0.41) | CNR2ITGA4ITGB7VNN1ALDH1A1 | |
| SCHEMBL9521077 | 0.95 | ALDH1A1 (0.41) | CNR2ITGA4ITGB7ALDH1A1LMNA | |
| SCHEMBL9490387 | 0.95 | ALDH1A1 (0.41) | CNR2ITGA4ITGB7ALDH1A1LMNA | |
| SCHEMBL9521837 | 0.94 | CYP2D6 (0.36) | CNR2ITGA4ITGB7ALDH1A1LMNA | |
| SCHEMBL9490420 | 0.94 | CYP2D6 (0.36) | CNR2ITGA4ITGB7ALDH1A1LMNA | |
| SCHEMBL9491119 | 0.92 | CYP2D6 (0.36) | CNR2ITGA4ITGB7ALDH1A1CYP2D6 | |
| SCHEMBL9521441 | 0.92 | CYP2D6 (0.36) | CNR2ITGA4ITGB7ALDH1A1CYP2D6 | |
| SCHEMBL9490797 | 0.92 | ALDH1A1 (0.39) | ALDH1A1LMNAP2RX7CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |
| EP-0390693-A1 | Thioformamide derivatives | RHONE-POULENC SANTE (FR) | 1990-10-03 | — | — | EP | disclosed |