Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663901 | 0.78 | TGM2 (0.48) | TGM2PTPN1PTPN11MMP1MMP2 | |
| SCHEMBL29366956 | 0.78 | MMP1 (0.59) | TGM2PTPN1PTPN11MMP1MMP2 | |
| SCHEMBL413017 | 0.78 | MMP1 (0.59) | TGM2PTPN1PTPN11MMP1MMP2 | |
| SCHEMBL9399365 | 0.77 | TDP1 (0.42) | RORCLMNABTK | |
| SCHEMBL8361130 | 0.76 | POLB (0.45) | TGM2MMP1MMP2MMP9RORC | |
| SCHEMBL1813156 | 0.76 | TGM2 (0.50) | TGM2PTPN1PTPN11RORCF13A1 | |
| SCHEMBL29588334 | 0.76 | TGM2 (0.50) | TGM2PTPN1PTPN11RORCF13A1 | |
| SCHEMBL7191119 | 0.76 | BTK (0.49) | TGM2PTPN1PTPN11MMP1MMP2 | |
| SCHEMBL14666462 | 0.76 | PTPN1 (0.53) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL6655989 | 0.75 | TGM2 (0.42) | TGM2PTPN1PTPN11GSTO1F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302293-A | Using a water soluble polymer containing pendant N-sulfoalkylene or -phenylene groups based on acrylic acid and/or amide groups; stabilizing suspensions; arctic region | NALCO CHEMICAL COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0330876-B1 | STABILIZATION OF IRON IN AQUEOUS SYSTEMS | NALCO CHEMICAL COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4869828-A | WATER SOLUBLE POLMYER HAVING SULFOALKYL AMIDE FUNCTIONALITY | NALCO CHEMICAL COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0330876-A1 | Stabilization of iron in aqueous systems | NALCO CHEMICAL COMPANY (US) | 1989-09-06 | — | — | EP | disclosed |