Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413017 | 0.85 | MMP1 (0.59) | TGM2PTPN1PTPN11MMP2MMP9 | |
| SCHEMBL29366956 | 0.85 | MMP1 (0.59) | TGM2PTPN1PTPN11MMP2MMP9 | |
| SCHEMBL8603981 | 0.83 | TGM2 (0.46) | TGM2PTPN1PTPN11GSTO1LMNA | |
| SCHEMBL14666462 | 0.82 | PTPN1 (0.53) | TGM2PTPN1PTPN11LMNAF13A1 | |
| SCHEMBL7191119 | 0.82 | BTK (0.49) | TGM2PTPN1PTPN11MMP2MMP9 | |
| SCHEMBL2355728 | 0.81 | KDM4E (0.55) | TGM2PTPN1PTPN11MMP2LMNA | |
| SCHEMBL613090 | 0.80 | TGM2 (0.65) | TGM2PTPN1PTPN11GSTO1LMNA | |
| SCHEMBL31228347 | 0.80 | TGM2 (0.65) | TGM2PTPN1PTPN11GSTO1LMNA | |
| SCHEMBL11331053 | 0.79 | TGM2 (0.53) | TGM2PTPN1PTPN11MMP2MMP9 | |
| SCHEMBL9399515 | 0.78 | TGM2 (0.42) | TGM2PTPN1PTPN11MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688287-A | Skin lightening agents comprising coumarins derived from resorcinol derivatives | UNILEVER PLC (NL) | 2005-10-26 | — | — | CN | disclosed |
| WO-2004017936-A1 | SKIN LIGHTENING AGENTS COMPRISING COUMARIN DERIVED FROM RESORCINOL DERIVATIVES | UNILEVER PLC (GB) | 2004-03-04 | — | — | WO | disclosed |