Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400123 | 0.77 | PTGS1 (0.46) | VCAM1 | |
| SCHEMBL9399916 | 0.72 | ALDH1A1 (0.35) | VCAM1 | |
| SCHEMBL9399938 | 0.70 | MAPT (0.37) | — | |
| SCHEMBL12240328 | 0.69 | HPGD (0.49) | MMP2ADAM17CA1CA2CA9 | |
| SCHEMBL19876726 | 0.69 | MTNR1A (0.52) | MMP2ADAM17MTNR1AMTNR1B | |
| SCHEMBL9399998 | 0.68 | POLB (0.45) | CA2 | |
| SCHEMBL9328163 | 0.67 | HPN (0.47) | VCAM1CA1CA2 | |
| SCHEMBL29128149 | 0.66 | ESRRB (0.47) | MMP2ADAM17ADRB2ADRB1ADRB3 | |
| SCHEMBL9399962 | 0.66 | POLB (0.34) | — | |
| SCHEMBL12264721 | 0.65 | MTNR1A (0.51) | MMP2ADAM17ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145970-A | Oil additives | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | claimed |
| US-5321067-A | Oxidation, heat resistance | CIBA-GEIGY CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| US-5145970-A | Oil additives | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |