Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400443 | 0.93 | MAPT (0.38) | MAPTALDH1A1MAPK1KMT2ATDP1 | |
| Diethylamine SCHEMBL9400354 | 0.91 | NR1H4 (0.40) | LMNAALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL9400372 | 0.91 | MAPT (0.38) | MAPTALDH1A1MAPK1KMT2ATDP1 | |
| SCHEMBL9400392 | 0.89 | MAPT (0.37) | MAPTLMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9400371 | 0.88 | MAPT (0.37) | MAPTLMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9400358 | 0.88 | MAPT (0.39) | MAPTLMNAALDH1A1MAPK1MEN1 | |
| SCHEMBL9400438 | 0.87 | PTGES (0.37) | MAPTLMNAALDH1A1MAPK1MEN1 | |
| SCHEMBL9400352 | 0.86 | ALDH1A1 (0.35) | MAPTLMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9400362 | 0.84 | MAPT (0.41) | MAPTLMNAALDH1A1MAPK1L3MBTL1 | |
| Diethylamine SCHEMBL9400448 | 0.84 | NR1H4 (0.36) | MAPTALDH1A1MEN1KMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372917-A | Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-12-13 | — | — | US | disclosed |