Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400372 | 0.98 | MAPT (0.38) | MAPTTSHRMAPK1HTTTP53 | |
| SCHEMBL9400392 | 0.96 | MAPT (0.37) | MAPTTSHRMAPK1TP53KMT2A | |
| SCHEMBL9400358 | 0.95 | MAPT (0.39) | MAPTTSHRMAPK1TP53KMT2A | |
| SCHEMBL9400438 | 0.95 | PTGES (0.37) | MAPTTSHRMAPK1HTTTP53 | |
| SCHEMBL9400371 | 0.94 | MAPT (0.37) | MAPTTSHRMAPK1HTTTP53 | |
| SCHEMBL9400350 | 0.93 | MAPT (0.44) | MAPTTSHRMAPK1HTTTP53 | |
| SCHEMBL9400352 | 0.91 | ALDH1A1 (0.35) | MAPTTSHRMAPK1TP53KMT2A | |
| Diethylamine SCHEMBL9400448 | 0.91 | NR1H4 (0.36) | MAPTTP53KMT2AKDM4EALDH1A1 | |
| SCHEMBL9400362 | 0.90 | MAPT (0.41) | MAPTTSHRMAPK1HTTKMT2A | |
| SCHEMBL9400491 | 0.89 | MAPT (0.41) | MAPTTSHRMAPK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372917-A | Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-12-13 | — | — | US | disclosed |