Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | PMM2 | O15305 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401001 | 0.85 | KAT2A (0.48) | HTR1AFAAHMGLL | |
| SCHEMBL9056742 | 0.80 | HTR1A (0.56) | DRD2DRD3HTR7ADRA1AHTR1A | |
| SCHEMBL9401019 | 0.79 | DRD2 (0.51) | DRD2DRD3DRD5HTR7ADRA1A | |
| SCHEMBL9400953 | 0.78 | DRD2 (0.49) | DRD2DRD3HTR7ADRA1AGRIN1 | |
| SCHEMBL9401056 | 0.78 | HTR1A (0.53) | DRD2DRD3HTR7ADRA1AHTR1A | |
| SCHEMBL9401035 | 0.77 | DRD2 (0.50) | DRD2DRD3DRD5HTR7ADRA1A | |
| SCHEMBL9480933 | 0.75 | HTR1A (0.71) | DRD2DRD3DRD5HTR7ADRA1A | |
| SCHEMBL9401027 | 0.73 | HTR1A (0.54) | DRD2DRD3DRD5HTR1AHTR2A | |
| SCHEMBL9400943 | 0.72 | HTR1A (0.61) | DRD2DRD3HTR7ADRA1AHTR1A | |
| Hydrochloric Acid SCHEMBL9376254 | 0.69 | HTR1A (0.65) | DRD2DRD3HTR7ADRA1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314884-A | Antidepressants, anxiolytic agents | TROPONWERKE GMBH & CO. (DE) | 1994-05-24 | — | — | US | disclosed |