Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751553 | 0.89 | MTNR1A (0.79) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL9401112 | 0.89 | MTNR1A (0.79) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL29138489 | 0.85 | MTNR1A (0.60) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL7692306 | 0.81 | KDM4E (0.56) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL30669507 | 0.80 | KDM4E (0.48) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL29138480 | 0.80 | ALB (0.51) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL29138474 | 0.80 | ALB (0.51) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL9401123 | 0.79 | KDM4E (0.44) | MTNR1AMTNR1BCYP2C19ALDH1A1MEN1 | |
| SCHEMBL29138500 | 0.78 | MTNR1A (0.88) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL30669508 | 0.78 | MTNR1A (0.88) | MTNR1AMTNR1BCYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |