SCHEMBL9401435

SCHEMBL9401435

COc1cc(OC)nc(SC(C)CO)n1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 1/20 0.36
ADORA3 P0DMS8 2/20 0.35
ALOX5 P09917 1/20 0.35
PPARG P37231 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ADORA1 P30542 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401193 0.83 ALDH1A1 (0.38) ALDH1A1CYP1A2ADORA3ALOX5PPARG
SCHEMBL9401526 0.81 ALDH1A1 (0.39) ALDH1A1CYP1A2ADORA3ALOX5PPARG
SCHEMBL9401293 0.80 ALDH1A1 (0.36) ALDH1A1ALOX5PPARG
SCHEMBL9411991 0.79 ALDH1A1 (0.38) ALDH1A1CYP1A2ADORA3LMNASMN1; SMN2
SCHEMBL9401194 0.79 ALOX5 (0.40) ALDH1A1CYP1A2ADORA3ALOX5PPARG
SCHEMBL9401418 0.79 ALDH1A1 (0.35) ALDH1A1ADORA3ALOX5PPARGADORA1
SCHEMBL10297587 0.79 TSHR (0.43) ALDH1A1CYP1A2LMNASMN1; SMN2KDM4E
SCHEMBL9401444 0.78 ALDH1A1 (0.37) ALDH1A1CYP1A2ADORA3LMNASMN1; SMN2
SCHEMBL9401391 0.77 ADORA3 (0.38) ALDH1A1ADORA3ALOX5PPARGADORA1
SCHEMBL9401363 0.77 ALDH1A1 (0.36) ALDH1A1CYP1A2ADORA3LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346880-A Pre- and postemergence NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0565951-A1 Herbicidally active pyrimidinylthioalkane derivatives NIHON BAYER AGROCHEM K.K. (JP) 1993-10-20 EP disclosed