Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | CASP1 | P29466 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033425 | 0.94 | HSD17B10 (0.69) | CACNA1BHSD17B10TSHRKDM4ECASP1 | |
| SCHEMBL11004996 | 0.88 | PKM (0.61) | CACNA1BHSD17B10TSHRKDM4ECASP1 | |
| SCHEMBL6951320 | 0.81 | ADORA3 (0.76) | CACNA1BHSD17B10TSHRKDM4EHPGD | |
| SCHEMBL27388698 | 0.81 | CACNA1B (0.60) | CACNA1BHSD17B10TSHRKDM4ECASP1 | |
| SCHEMBL3002791 | 0.81 | ADORA2B (0.67) | CACNA1BHSD17B10TSHRKDM4ECASP1 | |
| SCHEMBL7265410 | 0.80 | TSHR (0.65) | CACNA1BHSD17B10TSHRKDM4EHPGD | |
| SCHEMBL7158395 | 0.79 | ADORA3 (0.60) | CACNA1BHSD17B10TSHRKDM4EHPGD | |
| SCHEMBL9272854 | 0.78 | CACNA1F (0.69) | CACNA1BHSD17B10TSHRKDM4EHPGD | |
| SCHEMBL9401767 | 0.78 | KDM4E (0.68) | HSD17B10TSHRKDM4EHPGDADORA3 | |
| SCHEMBL27387459 | 0.78 | CACNA1B (0.56) | CACNA1BHSD17B10KDM4ECASP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |