Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26213958 | 0.74 | TAAR1 (0.50) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL7290701 | 0.71 | TAAR1 (0.54) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9433627 | 0.70 | TAAR1 (0.40) | TAAR1HTR1ATBXAS1ADRA2AADRA2B | |
| SCHEMBL7291454 | 0.69 | ADRA2A (0.50) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9433678 | 0.68 | TAAR1 (0.43) | TAAR1HTR1ATBXAS1ADRA2AADRA2B | |
| SCHEMBL7298246 | 0.67 | TAAR1 (0.42) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9401559 | 0.67 | TBXAS1 (0.69) | TBXAS1 | |
| SCHEMBL7299648 | 0.67 | TAAR1 (0.53) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9401567 | 0.67 | TBXAS1 (0.69) | TBXAS1 | |
| SCHEMBL7289609 | 0.65 | TAAR1 (0.50) | TAAR1HTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |