Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290701 | 0.75 | TAAR1 (0.54) | TAAR1HTR1AALDH1A1TSHRADRA2A | |
| SCHEMBL9434022 | 0.75 | TAAR1 (0.32) | TAAR1HTR1ACYP1A2CYP2D6CYP1B1 | |
| SCHEMBL9433627 | 0.72 | TAAR1 (0.40) | TAAR1HTR1AALDH1A1ADRA2AADRA2B | |
| SCHEMBL7291454 | 0.70 | ADRA2A (0.50) | TAAR1HTR1AALDH1A1TSHRADRA2A | |
| SCHEMBL7289609 | 0.69 | TAAR1 (0.50) | TAAR1HTR1AALDH1A1TSHRADRA2A | |
| SCHEMBL7299648 | 0.69 | TAAR1 (0.53) | TAAR1HTR1AALDH1A1TSHRADRA2A | |
| SCHEMBL7298246 | 0.69 | TAAR1 (0.42) | TAAR1HTR1AALDH1A1TSHRADRA2A | |
| SCHEMBL9401577 | 0.68 | TAAR1 (0.38) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL13372830 | 0.66 | TAAR1 (0.80) | TAAR1HTR1AALDH1A1TSHRADRA2A | |
| SCHEMBL7294989 | 0.65 | TAAR1 (0.48) | TAAR1HTR1ATSHRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |