Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401859 | 0.79 | TYMS (0.51) | TYMSKDM4ETSHRNR4A1NR4A2 | |
| SCHEMBL4108399 | 0.75 | ALDH1A1 (0.56) | KDM4ETSHRNR4A1NR4A2NR4A3 | |
| SCHEMBL2884593 | 0.75 | ALDH1A1 (0.45) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL475904 | 0.74 | TYMS (0.61) | TYMSKDM4ENR4A1NR4A2NR4A3 | |
| SCHEMBL4098387 | 0.70 | TSHR (0.63) | KDM4ETSHRNR4A1NR4A2NR4A3 | |
| SCHEMBL4960932 | 0.69 | TYMS (0.40) | TYMSKDM4ETSHRALDH1A1MEN1 | |
| SCHEMBL2694307 | 0.69 | TYMS (0.50) | TYMSKDM4ETSHRNR4A1NR4A2 | |
| SCHEMBL5795357 | 0.69 | WDR5 (0.53) | TYMSKDM4ETSHRNR4A1NR4A2 | |
| SCHEMBL9401930 | 0.69 | ALDH1A1 (0.42) | TYMSKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL6736118 | 0.69 | TYMS (0.54) | TYMSKDM4ENR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342739-A | Coating a substrate with a polyamic acid modified by an amino- or hydroxy-substituted phenol; shelf life | CHISSO CORPORATION (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0526650-A1 | PHOTOSENSITIVE POLYMER COMPOSITION AND PATTERN FORMATION | CHISSO CORPORATION (JP) | 1993-02-10 | — | — | EP | disclosed |