Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ELANE | P08246 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402942 | 0.88 | ELANE (0.41) | TDP1KDM4EELANENPC1HSD17B10 | |
| SCHEMBL9402777 | 0.86 | ELANE (0.36) | TDP1KDM4EELANE | |
| SCHEMBL9359013 | 0.84 | ELANE (0.39) | TDP1KDM4EELANENPC1HSD17B10 | |
| SCHEMBL9358950 | 0.81 | TDP1 (0.37) | TDP1KDM4EELANENPC1NR1H4 | |
| SCHEMBL9402644 | 0.81 | ELANE (0.41) | TDP1KDM4EELANEHSD17B10CDC25A | |
| SCHEMBL9402776 | 0.81 | KDM4E (0.47) | TDP1KDM4EELANEHSD17B10CDC25A | |
| SCHEMBL9402795 | 0.81 | TDP1 (0.39) | TDP1KDM4EELANENPC1HSD17B10 | |
| SCHEMBL9402901 | 0.80 | ELANE (0.36) | TDP1KDM4EELANENPC1HSD17B10 | |
| SCHEMBL9359357 | 0.79 | MAP2K1 (0.38) | TDP1ELANE | |
| SCHEMBL9402931 | 0.79 | RAB9A (0.48) | ELANEL3MBTL1NPC1NR1H4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |