Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402776 | 0.85 | KDM4E (0.47) | ELANEKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL9359013 | 0.83 | ELANE (0.39) | ELANEKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL9402689 | 0.82 | RAB9A (0.43) | ELANEKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9402914 | 0.82 | RAB9A (0.50) | KDM4ESRD5A2 | |
| SCHEMBL9402942 | 0.82 | ELANE (0.41) | ELANEKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL9402634 | 0.81 | TDP1 (0.38) | ELANEKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL9358950 | 0.80 | TDP1 (0.37) | ELANEKDM4ESRD5A2TDP1ALDH1A1 | |
| SCHEMBL9402795 | 0.80 | TDP1 (0.39) | ELANEKDM4EBCL2MCL1MAPK1 | |
| SCHEMBL9402901 | 0.79 | ELANE (0.36) | ELANEKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL9402931 | 0.78 | RAB9A (0.48) | ELANELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |