Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.71 |
| ▸ | CA2 | P00918 | 5/20 | 0.71 |
| ▸ | PLK1 | P53350 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.61 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14490986 | 0.89 | RAB9A (0.83) | NPC1RAB9ATP53SMN1; SMN2ALOX15 | |
| SCHEMBL13900091 | 0.85 | CA1 (0.62) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL407188 | 0.83 | CA1 (1.00) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL11705060 | 0.83 | MAPT (0.79) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL8717056 | 0.83 | PLK1 (0.80) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL13604055 | 0.82 | CA1 (0.66) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL13250861 | 0.82 | CA1 (0.50) | CA1CA2PLK1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4259929 | 0.82 | CA1 (0.96) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL28796093 | 0.81 | CA1 (0.62) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL28590876 | 0.81 | PLK1 (0.69) | PLK1NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735756-B | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-113292477-B | Method for synthesizing isoindole-1-ketone compound through iridium-catalyzed hydrocarbon activation reaction | 四川大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113149868-B | Method for synthesizing axichiral diene compound by trivalent rhodium catalysis | 陕西师范大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115433222-A | Preparation method and application of 2- (gem-difluoropropylene) benzamide compound | 五邑大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-113735756-A | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113149868-A | Method for synthesizing axial chiral allene compound by using trivalent rhodium as catalyst | 陕西师范大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-107082761-B | Phenanthridinone or benzophenanthridinone derivative and synthesis method thereof | 上海大学 | 2020-04-03 | — | — | CN | disclosed |
| US-8574463-B2 | Metal complex dye, photoelectric conversion element and dye-sensitized solar cell | FUJIFILM CORPORATION (JP) | 2013-11-05 | — | — | US | disclosed |
| US-20130087203-A1 | METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT AND DYE-SENSITIZED SOLAR CELL | FUJIFILM CORPORATION (JP) | 2013-04-11 | — | — | US | disclosed |
| EP-1049117-B1 | Ruthenium complex dye | FUJIFILM CORP (JP) | 2011-11-02 | — | — | EP | disclosed |
| EP-2280404-A2 | Metal complex dye for a photoelectrochemical cell | FUJIFILM Corporation (JP) | 2011-02-02 | — | — | EP | disclosed |
| EP-1666551-B1 | Ink for ink jet-recording curable through irradiation and method for preparing lithographic printing plates using the same | FUJIFILM CORP (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-7648997-B2 | Immunomodulators for inducing cytokine biosynthesis, for treatment of diseases including viral and neoplastic diseases; 1-[3-(Aminooxy)propyl]-2-propyl-1H-imidazo[4,5-c]quinolin-4-amine; N-[3-(4-Amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)propoxy]cyclopropanecarboxamide | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7648997-B2 | Immunomodulators for inducing cytokine biosynthesis, for treatment of diseases including viral and neoplastic diseases; 1-[3-(Aminooxy)propyl]-2-propyl-1H-imidazo[4,5-c]quinolin-4-amine; N-[3-(4-Amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)propoxy]cyclopropanecarboxamide | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-20080114019-A1 | Hydroxylamine Substituted Imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080114019-A1 | Hydroxylamine Substituted Imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-05-15 | — | — | US | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114019-A1 | Hydroxylamine Substituted Imidazoquinolines | IFNG, IRF3, IL2 | CA1 3424/4885CA2 4114/4885PLK1 3475/4885 |
| US-20130087203-A1 | METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT AND DYE-SENSITIZED SOLAR CELL | L1CAM, LSG1, CRY1 | CA1 376/4885CA2 142/4885PLK1 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.