Sugi Predict

Sugi Predict / Compounds / SCHEMBL407188

SCHEMBL407188

SCHEMBL407188

COc1ccc(C(=O)NN)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 4/20 1.00
▸ CA2 P00918 4/20 1.00
▸ ALDH1A1 P00352 4/20 0.75
▸ MAPT P10636 2/20 0.75
▸ HTT P42858 1/20 0.75
▸ PLK1 P53350 1/20 0.68
▸ NPC1 O15118 5/20 0.63
▸ RAB9A P51151 5/20 0.63
▸ SMN1; SMN2 Q16637 3/20 0.63
▸ TP53 P04637 2/20 0.63
▸ ALOX15 P16050 1/20 0.63
▸ PARP1 P09874 1/20 0.61
▸ PARP10 Q53GL7 1/20 0.61
▸ PARP2 Q9UGN5 1/20 0.61
▸ PARP4 Q9UKK3 1/20 0.61
▸ LMNA P02545 3/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ F10 P00742 1/20 0.59
▸ CES2 O00748 1/20 0.59
▸ CES1 P23141 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4259929 0.98 CA1 (0.96) CA1CA2ALDH1A1MAPTHTT
SCHEMBL7318116 0.94 CA1 (0.89) CA1CA2ALDH1A1MAPTHTT
SCHEMBL9377865 0.88 CA1 (0.77) CA1CA2ALDH1A1MAPTHTT
SCHEMBL3201438 0.87 ALDH1A1 (1.00) CA1CA2ALDH1A1MAPTHTT
SCHEMBL15595437 0.84 CA1 (0.72) CA1CA2ALDH1A1MAPTHTT
SCHEMBL8727275 0.84 CA1 (0.72) CA1CA2ALDH1A1MAPTHTT
SCHEMBL5693970 0.83 CA1 (0.71) CA1CA2ALDH1A1MAPTHTT
SCHEMBL9402885 0.83 CA1 (0.71) CA1CA2ALDH1A1MAPTPLK1
SCHEMBL8717056 0.83 PLK1 (0.80) CA1CA2ALDH1A1MAPTHTT
SCHEMBL4176758 0.83 CA1 (0.70) CA1CA2ALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080895-A Polyglycolic acid composition and preparation method thereof, biodegradable polyester material and application thereof, and PGA temporary plugging ball and preparation method thereof — 2026-05-26 — — CN claimed
CN-122037549-A Additive-based modified PLA composite material and preparation method thereof 江西伟恒数字科技有限公司 2026-05-15 — — CN claimed
CN-119977832-A Benzoyl hydrazine antineoplastic compound and preparation method and application thereof 江苏海洋大学 2025-05-13 — — CN claimed
CN-119431404-A Preparation method of FSP1 inhibitor FSEN3 江南大学 2025-02-14 — — CN claimed
CN-118812539-A 5-Aminotriazolopyrimidine derivative and preparation method thereof 苏州大学 2024-10-22 — — CN claimed
CN-118420534-A Naphthalimide sensor, preparation method thereof and application thereof in fluorescence detection of iron ions and copper ions 西北民族大学 2024-08-02 — — CN claimed
CN-116190116-B Capacitive carbon/lithium iron phosphate composite material and preparation method thereof 贵州胜泓威新材料科技有限公司 2024-02-13 — — CN claimed
CN-117402125-A Preparation method of noo Bo Suan oxadiazole thioester compound, product and application thereof 南京林业大学 2024-01-16 — — CN claimed
WO-2023209677-A2 A NOVEL ARYL AZO PYRAZOLE COMPOUND AND ITS SYNTHESIS ZENAL PHARMACHEM LLC (US) 2023-11-02 — — WO claimed
CN-116190116-A Capacitive carbon/lithium iron phosphate composite material and preparation method thereof 贵州胜泓威新材料科技有限公司 2023-05-30 — — CN claimed
US-20040106724-A1 Natural rubber produced from latex and composition comprising the same BRIDGESTONE CORPORATION (JP) 2004-06-03 — — US claimed
JP-2004514009-A — — 2004-05-13 — — JP claimed
EP-1332161-A2 DRYING PROCESSES FOR NATURAL RUBBER, STABILIZED NR COMPOSITIONS Bridgestone Corporation (JP) 2003-08-06 — — EP claimed
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-05 — — US claimed
US-6531527-B2 Liquid dilution after coagulation BRIDGESTONE CORPORATION (JP) 2003-03-11 — — US claimed
WO-2002102301-A2 SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-12-27 — — WO claimed
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2002-09-12 — — US claimed
WO-2002038667-A2 NATURAL RUBBER PRODUCED FROM LATEX AND COMPOSITION COMPRISING THE SAME BRIDGESTONE CORPORATION (JP) 2002-05-16 — — WO claimed
US-20020035195-A1 Viscosity-stabilizer-containing natural rubber latex and natural rubber and a production process thereof BRIDGESTONE CORPORATION 2002-03-21 — — US claimed
EP-0323590-A2 Carbazoyl derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1989-07-12 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 CA1 143/4885CA2 123/4885ALDH1A1 144/4885
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 CA1 143/4885CA2 123/4885ALDH1A1 144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.