Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | WDR5 | P61964 | 1/20 | 0.58 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.53 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487708 | 0.84 | WDR5 (0.73) | ALDH1A1MAPTMEN1KMT2AWDR5 | |
| SCHEMBL3553349 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL9818397 | 0.81 | WDR5 (0.69) | ALDH1A1MAPTMEN1KMT2AWDR5 | |
| SCHEMBL15045212 | 0.81 | KMT2A (0.69) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL2665022 | 0.81 | KMT2A (0.73) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL662338 | 0.79 | KMT2A (0.65) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL3561858 | 0.79 | MEN1 (0.65) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL15045213 | 0.79 | KMT2A (0.71) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL14549199 | 0.79 | KMT2A (0.61) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL9864681 | 0.79 | METAP2 (0.58) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336681-A | Elastase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |