SCHEMBL9818397

SCHEMBL9818397

O=C(O)c1cc(NS(=O)(=O)c2ccccc2)cc(NS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.69
TDP1 Q9NUW8 1/20 0.62
POLB P06746 2/20 0.62
PFKFB3 Q16875 1/20 0.61
IL1RN P18510 1/20 0.60
KEAP1 Q14145 1/20 0.60
ERAP1 Q9NZ08 1/20 0.60
CYTH2 Q99418 1/20 0.58
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 1/20 0.56
PKM P14618 1/20 0.56
AKR1C3 P42330 1/20 0.56
F2 P00734 1/20 0.55
F10 P00742 1/20 0.55
FURIN P09958 1/20 0.55
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
MAPT P10636 1/20 0.54
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10487708 0.96 WDR5 (0.73) WDR5TDP1POLBPFKFB3IL1RN
SCHEMBL711356 0.92 WDR5 (0.60) WDR5TDP1POLBPFKFB3IL1RN
SCHEMBL29261787 0.90 PFKFB3 (0.68) WDR5TDP1POLBPFKFB3IL1RN
SCHEMBL28538527 0.89 WDR5 (0.73) WDR5TDP1POLBPFKFB3IL1RN
SCHEMBL894613 0.86 POLB (0.82) POLBPFKFB3IL1RNKEAP1ERAP1
Zinc Ion SCHEMBL9420954 0.85 MEN1 (0.56) WDR5TDP1POLBPFKFB3IL1RN
SCHEMBL713275 0.84 CASP3 (0.60) WDR5TDP1POLBPFKFB3MEN1
SCHEMBL893905 0.84 CA12 (0.73) POLBIL1RNKEAP1ERAP1MEN1
SCHEMBL28678247 0.82 HDAC2 (0.60) WDR5POLBPFKFB3IL1RNKEAP1
Zinc Ion SCHEMBL9420962 0.81 WDR5 (0.59) WDR5POLBPFKFB3IL1RNKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308820-B1 ZINC, LEAD, AND/OR CALCIUMSALTS OF CARBOXYLIC ACIDS AND THEIR USE AS ANTICORROSIVE AGENTS BASF Lacke + Farben AG (DE) 1991-11-27 EP disclosed
US-4999134-A For alkyd resin coating systems, aqueous and nonaqueous BASF AKTIENGESELLSCHAFT (DE) 1991-03-12 US disclosed
EP-0308820-A1 Zinc, lead, and/or calciumsalts of carboxylic acids and their use as anticorrosive agents BASF Lacke + Farben AG (DE) 1989-03-29 EP disclosed