Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18335086 | 0.88 | MAPK1 (0.38) | MAPK1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL15142139 | 0.83 | ALDH1A1 (0.36) | MAPK1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL17476583 | 0.80 | MAPT (0.40) | KMT2AL3MBTL1MAPTCYP1A2CYP2C19 | |
| SCHEMBL5772798 | 0.80 | MAPT (0.35) | MAPK1KMT2AMEN1LMNAMAPT | |
| SCHEMBL18335075 | 0.79 | EGLN1 (0.38) | MAPK1KMT2AMEN1MAPT | |
| SCHEMBL4534445 | 0.77 | MAPT (0.37) | KMT2AMAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL12985302 | 0.77 | MAPT (0.38) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL896209 | 0.76 | MEN1 (0.56) | MAPK1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL895506 | 0.75 | L3MBTL1 (0.42) | MAPK1L3MBTL1LMNABCHELIPE | |
| SCHEMBL7691831 | 0.73 | MAPT (0.43) | KMT2AMEN1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254416-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2016-09-07 | — | — | EP | disclosed |
| US-8653078-B2 | Herbicidal pyrido[2,3-b]pyrazines | SYNGENTA LIMITED | 2014-02-18 | — | — | US | disclosed |
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-05-30 | — | — | US | disclosed |
| US-8338598-B2 | Herbicidal pyrido[2,3-B]pyrazines and their use as herbicides | SYNGENTA LIMITED | 2012-12-25 | — | — | US | disclosed |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2254416-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009090402-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, CBR1 | MAPK1 171/4885KMT2A 2153/4885MEN1 3263/4885 |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, TH | MAPK1 157/4885KMT2A 1132/4885MEN1 3200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.