Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175379 | 0.85 | TXNRD1 (0.54) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL553682 | 0.84 | TXNRD1 (0.56) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL1269639 | 0.84 | CYP1A2 (0.56) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL24584925 | 0.84 | TXNRD1 (0.52) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL9403358 | 0.84 | GAA (0.58) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL24323271 | 0.84 | ALDH1A1 (0.56) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8517079 | 0.82 | ALDH1A1 (0.58) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL24584923 | 0.82 | TXNRD1 (0.51) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL5176555 | 0.82 | TXNRD1 (0.51) | TXNRD1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL3056874 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1MEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022137240-A1 | METHACRYLAMIDES PROTEIN BINDERS AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-06-30 | — | — | WO | disclosed |
| EP-0933682-B1 | Radiation-sensitive compositions with binders of polymers comprising N-substituted maleimide units | AGFA GEVAERT (BE) | 2006-08-09 | — | — | EP | disclosed |
| US-6190825-B1 | N-(P-AMINOSULFONYL)PHENYL-SUBSTITUTED | AGFA-GEVAERT N.V. (BE) | 2001-02-20 | — | — | US | disclosed |
| EP-0933682-A2 | Polymers comprising N-substituted maleimide units and their use in radiation-sensitive compositions | Agfa-Gevaert AG (DE) | 1999-08-04 | — | — | EP | disclosed |