SCHEMBL940371

SCHEMBL940371

C=COCCOc1c(F)c(F)c(C(=O)O)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP2C9 P11712 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4360669 0.98 TSHR (0.33) TSHRSMN1; SMN2POLBMAPTTDP1
SCHEMBL4360667 0.84 CA1 (0.34)
SCHEMBL6832256 0.82
SCHEMBL14589426 0.77
SCHEMBL8563080 0.75
SCHEMBL1583078 0.72 THRA (0.47) TSHR
SCHEMBL1938845 0.71
SCHEMBL27830419 0.71 THRB (0.41) TSHRSMN1; SMN2POLBMAPTTDP1
SCHEMBL8567444 0.70 ESR1 (0.45) TSHR
SCHEMBL9861359 0.70 ESR1 (0.38) TSHRSMN1; SMN2POLBMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7866806-B2 Liquid-composition set, and liquid-applying method and liquid-applying apparatus employing the set CANON KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
US-20060146087-A1 Liquid, ph-sensitive ink, method and apparatus using the same CANON KABUSHIKI KAISHA (JP) 2006-07-06 US disclosed
WO-2005085370-A1 IMAGE FORMING METHOD, PATTERN FORMING METHOD AND LIQUID-APPLYING APPARATUS WHICH MAKE USE OF LIQUID COMPOSITIONS CANON KABUSHIKI KAISHA (JP) 2005-09-15 WO disclosed
WO-2004106440-A1 LIQUID, PH-SENSITIVE INK, METHOD AND APPARATUS USING THE SAME CANON KABUSHIKI KAISHA (JP) 2004-12-09 WO disclosed