Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034123 | 0.87 | PDE3B (0.66) | PDE3BPDE3ANR3C1PGRSLC6A4 | |
| SCHEMBL8500022 | 0.80 | PDE3B (0.65) | PDE3BPDE3ANR3C1PGRSLC6A4 | |
| SCHEMBL11206168 | 0.75 | LMNA (0.74) | PDE3BPDE3ANR3C1PGRSLC6A4 | |
| SCHEMBL10590870 | 0.74 | PDE3B (0.74) | PDE3BPDE3ANR3C1PGRSLC6A4 | |
| SCHEMBL9412183 | 0.73 | POLB (0.58) | PDE3BPDE3ASMN1; SMN2LMNAGAA | |
| SCHEMBL9824612 | 0.73 | PDE3B (0.83) | PDE3BPDE3ANR3C1PGRSLC6A4 | |
| SCHEMBL9412162 | 0.73 | LMNA (0.56) | PDE3BPDE3ASMN1; SMN2LMNAGAA | |
| SCHEMBL9693701 | 0.73 | PDE3B (1.00) | PDE3BPDE3ANR3C1PGRSLC6A4 | |
| SCHEMBL16276101 | 0.73 | LMNA (0.64) | PDE3BPDE3ANR3C1PGRSLC6A4 | |
| Vesnarinone SCHEMBL6243858 | 0.73 | PDE3B (1.00) | PDE3BPDE3ANR3C1PGRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6179621-A | — | — | None | — | — | JP | disclosed |
| JP-H06179621-A | ANTICANCER AGENT | OTSUKA PHARMACEUT CO LTD | 1994-06-28 | — | — | JP | disclosed |