Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 4/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997493 | 0.91 | MMP2 (0.47) | MMP2MMP9MMP3EPHX2 | |
| SCHEMBL379441 | 0.91 | MMP2 (0.47) | MMP2MMP9MMP3EPHX2 | |
| SCHEMBL2307573 | 0.91 | MMP2 (0.47) | MMP2MMP9MMP3EPHX2 | |
| SCHEMBL8333912 | 0.89 | MMP2 (0.46) | MMP2MMP9MMP3 | |
| Guanidine SCHEMBL9509189 | 0.85 | MMP2 (0.41) | MMP2MMP9MMP3NAAA | |
| SCHEMBL11140706 | 0.84 | OPRM1 (0.46) | MMP2MMP9MMP3PKMALOX12 | |
| SCHEMBL27885042 | 0.77 | KDM1A (0.38) | — | |
| SCHEMBL10812665 | 0.77 | KDM1A (0.38) | — | |
| Water SCHEMBL28147213 | 0.74 | MMP2 (0.41) | MMP2MMP9MMP3MEN1GAA | |
| SCHEMBL27541138 | 0.72 | MMP2 (0.42) | MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358338-B1 | Method and composition for surface treatment | ALCAN INT LTD (CA) | 1994-07-27 | — | — | EP | disclosed |
| EP-0396238-A1 | Method for treating aluminium surfaces | ALCAN INTERNATIONAL LIMITED (CA) | 1990-11-07 | — | — | EP | disclosed |
| EP-0358338-A2 | Method and composition for surface treatment | ALCAN INTERNATIONAL LIMITED (CA) | 1990-03-14 | — | — | EP | disclosed |