Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404475 | 0.90 | GABRA1 (0.44) | GABRA1GABRB2GABRA3GABRA6CNR2 | |
| SCHEMBL9429847 | 0.86 | GABRA1 (0.41) | GABRA1GABRB2GABRA3GABRA6LRRK2 | |
| SCHEMBL9430333 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2GABRA3GABRA6LRRK2 | |
| SCHEMBL9429999 | 0.86 | HTR3E (0.44) | GABRA1GABRB2GABRA3GABRA6DGAT1 | |
| SCHEMBL9404245 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2GABRA3GABRA6 | |
| SCHEMBL9404451 | 0.85 | OPRK1 (0.37) | GABRA1GABRB2GABRA3GABRA6LRRK2 | |
| SCHEMBL7321094 | 0.85 | GABRA1 (0.48) | GABRA1GABRB2GABRA3GABRA6 | |
| SCHEMBL9430479 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2GABRA3GABRA6 | |
| SCHEMBL9430428 | 0.84 | PIK3CA (0.35) | GABRA1GABRB2GABRA3GABRA6LRRK2 | |
| SCHEMBL9404253 | 0.83 | GABRA1 (0.44) | GABRA1GABRB2GABRA3GABRA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371080-A | Central nervous system disorders | NOVO NORDISK A/S | 1994-12-06 | — | — | US | disclosed |
| EP-0619820-A1 | IMIDAZOQUINAZOLINE COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993013103-A1 | IMIDAZOQUINAZOLINE COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-07-08 | — | — | WO | disclosed |