Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330158 | 0.77 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL9380265 | 0.71 | MEN1 (0.48) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL29468686 | 0.71 | MEN1 (0.48) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL31253221 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL10477389 | 0.70 | ALOX15 (0.48) | KDM4EALDH1A1HTTPOLBMAPT | |
| SCHEMBL15465667 | 0.70 | TSHR (0.56) | KDM4EALDH1A1HTTCYP1A2POLB | |
| SCHEMBL4296230 | 0.70 | HSD17B10 (0.61) | KDM4EALDH1A1HPGDRECQLCYP1A2 | |
| SCHEMBL7072038 | 0.69 | KDM5A (0.48) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL2445509 | 0.69 | GABRA1 (0.52) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL2445674 | 0.69 | HRH4 (0.53) | KDM4EALDH1A1HPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502885-B1 | IMIDAZOQUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1994-06-01 | — | — | EP | disclosed |
| EP-0502885-A1 | IMIDAZOQUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1992-09-16 | — | — | EP | disclosed |
| US-5102885-A | Anticonvulsants, anxiolytic agents, cognition activators | NOVO NORDISK A/S (DK) | 1992-04-07 | — | — | US | disclosed |
| WO-1991007408-A1 | IMIDAZOQUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-05-30 | — | — | WO | disclosed |