Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23574683 | 0.82 | MAPT (0.55) | MAPT | |
| SCHEMBL9671700 | 0.77 | HRH3 (0.74) | HRH3KCNH2SIGMAR1LMNALSS | |
| SCHEMBL9670561 | 0.75 | SIGMAR1 (0.64) | HRH3KCNH2SIGMAR1LMNATAAR1 | |
| SCHEMBL28571095 | 0.75 | TDP1 (0.39) | MAPTAKT2 | |
| SCHEMBL10176696 | 0.74 | METAP2 (0.55) | MAPTLMNA | |
| SCHEMBL16766999 | 0.73 | LMNA (0.36) | MAPTLMNA | |
| SCHEMBL6520645 | 0.71 | FYN (0.39) | — | |
| SCHEMBL20575158 | 0.71 | METAP2 (0.34) | MAPT | |
| SCHEMBL17091200 | 0.71 | HRH3 (0.50) | HRH3TAAR1AKT2 | |
| SCHEMBL26785656 | 0.71 | METAP2 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6206872-A | — | — | None | — | — | JP | disclosed |
| JP-H06206872-A | CONDENSED TYPE PYRAZOLE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1994-07-26 | — | — | JP | disclosed |