Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD3 | P35462 | 6/20 | 0.39 |
| ▸ | HTR1D | P28221 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD5 | P21918 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406456 | 0.75 | HTR1D (0.44) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL16661438 | 0.70 | SLC6A9 (0.43) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL1874690 | 0.70 | DRD2 (0.39) | DRD2DRD3HTR1DDRD4CHRM1 | |
| SCHEMBL4101028 | 0.68 | DRD3 (0.67) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL10011429 | 0.68 | PPARD (0.62) | — | |
| SCHEMBL14673522 | 0.67 | SLC6A9 (0.39) | DRD2DRD3 | |
| SCHEMBL21270524 | 0.67 | CA2 (0.38) | DRD2DRD3HTR1DDRD4HTR1A | |
| SCHEMBL21270522 | 0.67 | CA2 (0.38) | DRD2DRD3HTR1DDRD4HTR1A | |
| SCHEMBL21178299 | 0.67 | PPARG (0.38) | DRD2DRD3HTR1DHSD11B1 | |
| SCHEMBL1874689 | 0.67 | DRD2 (0.37) | DRD2DRD3HTR1DDRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617618-A1 | ARYL-TRIFLATES AND RELATED COMPOUNDS | WIKSTRÖM, Hakan Vilhelm (NL) | 1994-10-05 | — | — | EP | disclosed |
| WO-1993011761-A1 | ARYL-TRIFLATES AND RELATED COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-24 | — | — | WO | disclosed |