Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR1B | P28222 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627910 | 0.81 | HTR1A (0.44) | HTR1AHTR1BDRD2DRD3DRD4 | |
| SCHEMBL9627777 | 0.78 | PPARG (0.37) | HTR1DHTR1AHTR1BDRD2DRD1 | |
| SCHEMBL9628958 | 0.75 | PPARG (0.39) | HTR1DHTR1A | |
| SCHEMBL9406461 | 0.75 | DRD2 (0.39) | HTR1DHTR1AHTR1BDRD2DRD3 | |
| SCHEMBL9628089 | 0.74 | ACHE (0.41) | — | |
| SCHEMBL9627835 | 0.74 | DRD3 (0.46) | DRD2DRD3DRD4 | |
| Oxalic Acid SCHEMBL9628990 | 0.74 | ACHE (0.39) | — | |
| SCHEMBL9627868 | 0.72 | KMT2A (0.41) | HTR1AHTR1BDRD2DRD1 | |
| Oxalic Acid SCHEMBL9628716 | 0.72 | ACHE (0.46) | — | |
| SCHEMBL9628742 | 0.72 | TP53 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617618-A1 | ARYL-TRIFLATES AND RELATED COMPOUNDS | WIKSTRÖM, Hakan Vilhelm (NL) | 1994-10-05 | — | — | EP | disclosed |
| WO-1993011761-A1 | ARYL-TRIFLATES AND RELATED COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-24 | — | — | WO | disclosed |