Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428138 | 0.86 | ACHE (0.41) | RIPK1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9427965 | 0.83 | USP2 (0.36) | RIPK1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8782099 | 0.82 | HTR2A (0.44) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8783196 | 0.76 | ESR1 (0.45) | ESR1ESR2MAPTDRD2MAPK1 | |
| SCHEMBL9429146 | 0.69 | HRH3 (0.36) | RIPK1PRKCZHPGD | |
| SCHEMBL9427669 | 0.66 | TSHR (0.38) | RIPK1PRKCZ | |
| SCHEMBL7598342 | 0.66 | AR (0.71) | ESR1ESR2MAPTCYP1A2MAPK1 | |
| SCHEMBL29678628 | 0.65 | PBRM1 (0.53) | PBRM1CRBNDRD2KMT2AMEN1 | |
| SCHEMBL1037654 | 0.65 | PBRM1 (0.53) | PBRM1CRBNDRD2KMT2AMEN1 | |
| SCHEMBL8782370 | 0.64 | DRD2 (0.39) | RIPK1PRKCZHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6211798-A | — | — | None | — | — | JP | disclosed |
| JP-H06211798-A | TETRAHYDROISOQUINOLINE DERIVATIVE AND ITS PRODUCTION | TOSOH CORP | 1994-08-02 | — | — | JP | disclosed |