Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153563 | 0.80 | MAPT (0.49) | MAPTCYP1A2POLBCYP2C9CYP2C19 | |
| SCHEMBL37520 | 0.71 | MAPT (0.56) | ALOX5MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8567536 | 0.67 | CUL4A (0.39) | ALOX5MAPTCYP1A2RAB9AHPGD | |
| SCHEMBL16702759 | 0.67 | ALDH1A1 (0.43) | ALOX5MAPTCYP1A2NPC1HPGD | |
| SCHEMBL27861489 | 0.66 | MAPT (0.54) | MAPTCYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL11118774 | 0.66 | MAPT (0.48) | ALOX5MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13195034 | 0.66 | POLB (0.45) | MAPTCYP1A2POLBCYP2C9CYP2C19 | |
| SCHEMBL9407230 | 0.66 | POLB (0.45) | ALOX5MAPTPOLBNPC1RAB9A | |
| Urethane SCHEMBL21771895 | 0.65 | ALOX15 (0.52) | MAPTCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL21991771 | 0.65 | MMP2 (0.53) | MAPTCYP1A2L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601386-A1 | Sulphonamides | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | disclosed |