SCHEMBL8567536

SCHEMBL8567536

CCOC(=O)Oc1nc(Cl)c(C)c(Cl)c1OC(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CUL4A Q13619 2/20 0.39
ALDH1A1 P00352 3/20 0.36
ALOX5 P09917 1/20 0.36
SOAT1 P35610 1/20 0.34
KDM4E B2RXH2 3/20 0.32
KDM5B Q9UGL1 1/20 0.32
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30
CYP1A2 P05177 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569899 0.85 CUL4A (0.40) CUL4AALDH1A1ALOX5SOAT1KDM4E
SCHEMBL11140980 0.74 ALDH1A1 (0.50) CUL4AALDH1A1SOAT1KDM4EMEN1
SCHEMBL8567975 0.72 ALDH1A1 (0.36) CUL4AALDH1A1ALOX5SOAT1HPGD
SCHEMBL8559572 0.71 CUL4A (0.41) CUL4AALDH1A1ALOX5SOAT1MEN1
SCHEMBL4070899 0.69 ALDH1A1 (0.40) CUL4AALDH1A1ALOX5SOAT1KDM4E
SCHEMBL10438826 0.69 ALDH1A1 (0.40) CUL4AALDH1A1ALOX5SOAT1KDM4E
SCHEMBL9191295 0.69 ALOX5 (0.39) CUL4AALDH1A1ALOX5SOAT1KDM4E
SCHEMBL8312577 0.68 PDE4D (0.45) CUL4AALDH1A1SOAT1KDM4EHPGD
SCHEMBL1542274 0.68 ACHE (0.38) ALDH1A1ALOX5KDM4EHPGDMAPT
SCHEMBL9407239 0.67 ALOX5 (0.43) ALDH1A1ALOX5KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661282-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-04-22 EP disclosed
EP-0661282-A1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed