Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21880277 | 0.86 | LMNA (0.37) | LTA4HACHEMAPTMAOA | |
| SCHEMBL5584000 | 0.81 | ATM (0.40) | ATMOPRM1OPRL1TRPA1CA4 | |
| SCHEMBL5583991 | 0.80 | CHRM3 (0.46) | ATMOPRM1OPRL1TRPA1CA4 | |
| SCHEMBL30886749 | 0.80 | OPRM1 (0.42) | ATMOPRM1OPRL1TRPA1CA4 | |
| SCHEMBL30825751 | 0.80 | CHRM3 (0.46) | ATMOPRM1OPRL1TRPA1CA4 | |
| SCHEMBL3729918 | 0.80 | ALOX5 (0.38) | P2RX4MAOAMAOB | |
| SCHEMBL23423294 | 0.76 | ATM (0.37) | ATMOPRM1OPRL1TRPA1CA4 | |
| SCHEMBL11451696 | 0.75 | MAPT (0.46) | MAPTMAOAMAOB | |
| SCHEMBL21204876 | 0.73 | CYP2A6 (0.49) | TRPA1MAPT | |
| SCHEMBL31237209 | 0.72 | MAPT (0.43) | ATMOPRM1OPRL1CA4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624372-A2 | Medicament for treating human immunodeficiency virus | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |
| EP-0617046-A1 | Nucleoside derivatives and antiherpes composition | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |