Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663165 | 0.76 | ALDH1A1 (0.39) | TP53NAMPTALDH1A1TSHRALOX15 | |
| SCHEMBL7659195 | 0.73 | HDAC1 (0.39) | TP53NAMPTMEN1KMT2AHPGD | |
| SCHEMBL7748302 | 0.72 | NAMPT (0.36) | TP53NAMPTMEN1KMT2AHPGD | |
| SCHEMBL7742689 | 0.68 | HDAC1 (0.40) | TP53NAMPTMEN1KMT2AHPGD | |
| SCHEMBL29410885 | 0.65 | NAMPT (0.57) | TP53NAMPTHPGDALDH1A1HDAC1 | |
| SCHEMBL7668002 | 0.65 | NAMPT (0.37) | TP53NAMPTMEN1KMT2AKDM4E | |
| SCHEMBL7663172 | 0.64 | ALOX15 (0.46) | TP53NAMPTALDH1A1TSHRALOX15 | |
| SCHEMBL751001 | 0.64 | TP53 (0.49) | TP53NAMPTMEN1KMT2AHPGD | |
| SCHEMBL7746804 | 0.63 | HDAC1 (0.38) | TP53NAMPTMEN1KMT2AHPGD | |
| SCHEMBL13159486 | 0.63 | TP53 (0.51) | TP53NAMPTHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |