Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407953 | 1.00 | TSHR (0.40) | TSHRUSP2ALDH1A1HSD17B10MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL9407957 | 0.99 | TSHR (0.39) | TSHRUSP2ALDH1A1HSD17B10MAPKAPK2 | |
| SCHEMBL13099208 | 0.87 | MAPT (0.42) | USP2MAPKAPK2ABL1ACVR1USP28 | |
| Hydrochloric Acid SCHEMBL9408126 | 0.86 | MAPT (0.41) | USP2MAPKAPK2ABL1ACVR1USP28 | |
| Hydrochloric Acid SCHEMBL9408037 | 0.84 | LGMN (0.45) | ALDH1A1ACVR1NPC1USP28USP25 | |
| SCHEMBL9244763 | 0.83 | NPC1 (0.50) | TSHRCSNK2A2CSNK2A1PARP1PARP2 | |
| SCHEMBL9244757 | 0.83 | NPC1 (0.50) | TSHRCSNK2A2CSNK2A1PARP1PARP2 | |
| SCHEMBL9407966 | 0.82 | HTR2A (0.55) | TSHRUSP2ALDH1A1MAPT | |
| SCHEMBL9407965 | 0.82 | HTR2A (0.55) | TSHRUSP2ALDH1A1MAPT | |
| SCHEMBL13098786 | 0.82 | MAPT (0.38) | TSHRUSP2ALDH1A1CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |