Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.37 |
| ▸ | USP25 | Q9UHP3 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9408126 | 0.99 | MAPT (0.41) | MAPTMAPKAPK2ACVR1TGFBR1PDE3B | |
| Hydrochloric Acid SCHEMBL9408037 | 0.88 | LGMN (0.45) | MAPTACVR1KMT2ASMN1; SMN2USP28 | |
| SCHEMBL9407948 | 0.87 | TSHR (0.40) | MAPTMAPKAPK2ACVR1TGFBR1USP2 | |
| SCHEMBL9407953 | 0.87 | TSHR (0.40) | MAPTMAPKAPK2ACVR1TGFBR1USP2 | |
| SCHEMBL3101680 | 0.87 | MAPT (0.43) | MAPTPDE3BPDE3AUSP2MEN1 | |
| Hydrochloric Acid SCHEMBL9407957 | 0.86 | TSHR (0.39) | MAPTMAPKAPK2ACVR1TGFBR1USP2 | |
| SCHEMBL13098780 | 0.84 | MAPT (0.41) | MAPTPDE3BPDE3AUSP2MEN1 | |
| SCHEMBL9407972 | 0.84 | DGAT1 (0.41) | ACVR1TGFBR1USP25 | |
| SCHEMBL9407975 | 0.84 | DGAT1 (0.41) | ACVR1TGFBR1USP25 | |
| SCHEMBL13099157 | 0.84 | HRH3 (0.42) | MAPTPDE3BPDE3AUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256048-A1 | POLYPEPTIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256048-A1 | POLYPEPTIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256048-A1 | POLYPEPTIDE COMPOUND | VIP, ANPEP, NPEPPS | MAPT 3126/4885MAPKAPK2 2698/4885ACVR1 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.