Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408072 | 1.00 | GABRP (0.41) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Hydrochloric Acid SCHEMBL9407980 | 0.81 | ALDH1A1 (0.41) | HPGDKMT2ASMN1; SMN2CHRM1ALDH1A1 | |
| SCHEMBL4155085 | 0.78 | TSHR (0.61) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL11213370 | 0.71 | TSHR (0.56) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL7362647 | 0.71 | GABRP (0.44) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL7362650 | 0.71 | GABRP (0.44) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL9407948 | 0.70 | TSHR (0.40) | TSHRALDH1A1PARP1MAPT | |
| SCHEMBL9244763 | 0.70 | NPC1 (0.50) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL9244757 | 0.70 | NPC1 (0.50) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Hydrochloric Acid SCHEMBL9407957 | 0.69 | TSHR (0.39) | TSHRALDH1A1PARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |