Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810785 | 0.80 | GPR174 (0.40) | MAPTTP53HTTALDH1A1TDP1 | |
| SCHEMBL8806549 | 0.78 | MAPT (0.51) | MAPTHTTALDH1A1TDP1GPR174 | |
| SCHEMBL25845895 | 0.69 | MAPT (0.78) | MAPTTP53HTTALDH1A1TDP1 | |
| SCHEMBL13648194 | 0.68 | MAPT (0.64) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL20594914 | 0.68 | AKR1B1 (0.52) | MAPTHTTALDH1A1CTSBTDP1 | |
| SCHEMBL20522603 | 0.67 | MAPT (0.63) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL13999700 | 0.67 | MAPT (0.75) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL6509839 | 0.66 | MAPT (0.62) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL3435055 | 0.66 | MAPT (0.74) | MAPTTP53HTTALDH1A1CTSB | |
| SCHEMBL6529147 | 0.66 | MAPT (0.68) | MAPTTP53HTTALDH1A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6298756-A | — | — | None | — | — | JP | disclosed |
| JP-H06298756-A | PIPERIDINO-3,4-DIHYDROCARBOSTYRYL DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1994-10-25 | — | — | JP | disclosed |