Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392562 | 0.83 | AKR1B1 (0.49) | MAPTALDH1A1TDP1CYP3A4LMNA | |
| SCHEMBL8810785 | 0.81 | GPR174 (0.40) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8805728 | 0.80 | LMNA (0.44) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL8805822 | 0.80 | LMNA (0.42) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8808373 | 0.80 | DRD2 (0.39) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8805609 | 0.80 | HSP90AA1 (0.37) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8806081 | 0.80 | DRD2 (0.42) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9408149 | 0.78 | MAPT (0.47) | MAPTALDH1A1TDP1LMNAGPR174 | |
| SCHEMBL20594914 | 0.78 | AKR1B1 (0.52) | MAPTALDH1A1TDP1CYP3A4LMNA | |
| SCHEMBL8805973 | 0.77 | PDE3B (0.43) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6065232-A | — | — | None | — | — | JP | disclosed |
| EP-0583136-B1 | Piperidino-3,4-dihydrocarbostyryl compounds for the treatment of ischemic disorders | KISSEI PHARMACEUTICAL (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5294718-A | Platelet aggregation inhibitors; antiischemic agents; side effect reduction | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| JP-H0665232-A | PIPERIDINO-3,4-DIHYDROCARBOSTYRYL DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1994-03-08 | — | — | JP | disclosed |
| EP-0583136-A2 | Piperidino-3,4-dihydrocarbostyryl compounds for the treatment of ischemic disorders | Kissei Pharmaceutical Co., Ltd. (JP) | 1994-02-16 | — | — | EP | disclosed |