SCHEMBL9408689

SCHEMBL9408689

COc1cc(OC)nc(SC(COC(=O)CCC(=O)OCC(Sc2nc(OC)cc(OC)n2)C(C)(C)C)C(C)(C)C)n1.[NaH].[NaH]

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP1A2 P05177 1/20 0.33
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9408634 0.93 ADORA3 (0.37) ALDH1A1L3MBTL1ADORA3
SCHEMBL9408697 0.92 L3MBTL1 (0.33) ALDH1A1L3MBTL1ADORA3
SCHEMBL9408626 0.91 L3MBTL1 (0.36) ALDH1A1L3MBTL1ADORA3
SCHEMBL9408696 0.90 ALDH1A1 (0.36) ALDH1A1CYP1A2ADORA3
SCHEMBL9408865 0.88 ALDH1A1 (0.39) ALDH1A1CYP1A2ADORA3
SCHEMBL9408733 0.87 ALDH1A1 (0.38) ALDH1A1CYP1A2ADORA3
SCHEMBL9408609 0.82 TSHR (0.38) ALDH1A1CYP1A2ADORA3
SCHEMBL9408667 0.82 ALDH1A1 (0.33) ALDH1A1CYP1A2ADORA3
SCHEMBL9408686 0.81 TSHR (0.43) ALDH1A1
SCHEMBL9408616 0.81 ALDH1A1 (0.44) ALDH1A1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0593998-A1 Pyrimidinylthioalkane herbicides NIHON BAYER AGROCHEM K.K. (JP) 1994-04-27 EP disclosed