Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508460 | 0.84 | NPC1 (0.62) | NPC1RAB9ALMNAPOLBMEN1 | |
| SCHEMBL9408769 | 0.84 | NPC1 (0.51) | NPC1RAB9ALMNAPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL8372133 | 0.82 | NPC1 (0.61) | NPC1RAB9ALMNAPOLBMEN1 | |
| SCHEMBL9408808 | 0.82 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBMEN1 | |
| SCHEMBL9408768 | 0.80 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBMEN1 | |
| SCHEMBL9408845 | 0.80 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBKMT2A | |
| SCHEMBL9408834 | 0.80 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL9408926 | 0.80 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBMEN1 | |
| SCHEMBL9408810 | 0.77 | NPC1 (0.39) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL9437913 | 0.77 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |