Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408798 | 0.84 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL508460 | 0.82 | NPC1 (0.62) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8372133 | 0.81 | NPC1 (0.61) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408808 | 0.81 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL563223 | 0.80 | NPC1 (0.71) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408883 | 0.79 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408834 | 0.79 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408768 | 0.79 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408845 | 0.79 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408926 | 0.78 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |