Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618684 | 0.73 | KDM4E (0.56) | L3MBTL1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL12844265 | 0.72 | LRRK2 (0.39) | L3MBTL1ALDH1A1KDM4ELRRK2SMN1; SMN2 | |
| SCHEMBL8930739 | 0.71 | ALDH1A1 (0.40) | L3MBTL1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL9432628 | 0.68 | RAB9A (0.50) | L3MBTL1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL197559 | 0.68 | LRRK2 (0.48) | HPGDALDH1A1LRRK2SMN1; SMN2RAB9A | |
| SCHEMBL27711178 | 0.67 | RAB9A (0.39) | HPGDALDH1A1KDM4EGAAMAPT | |
| SCHEMBL21995607 | 0.67 | KMT2A (0.45) | L3MBTL1ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL9353795 | 0.66 | SMN1; SMN2 (0.50) | L3MBTL1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL4266239 | 0.66 | CYP11B1 (0.36) | HPGDALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL10803722 | 0.66 | CA12 (0.34) | L3MBTL1HPGDALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623601-A1 | N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-11-09 | — | — | EP | disclosed |