Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080032 | 0.77 | TDP1 (0.42) | TDP1CYP2D6LMNATSHRALOX12 | |
| SCHEMBL19713142 | 0.65 | CYP2D6 (0.38) | CYP2D6LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL2980082 | 0.65 | TAAR1 (0.34) | TDP1CYP2D6ALDH1A1TAAR1SLC6A2 | |
| SCHEMBL2968167 | 0.65 | — | — | |
| SCHEMBL2976898 | 0.65 | TSHR (0.39) | TDP1LMNATSHRALOX12ALDH1A1 | |
| SCHEMBL49939 | 0.63 | ALDH1A1 (0.40) | TDP1LMNATSHRALOX12ALDH1A1 | |
| SCHEMBL8524658 | 0.63 | ALDH1A1 (0.40) | TDP1LMNATSHRALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15771658 | 0.63 | TSHR (0.37) | TDP1LMNATSHRALOX12ALDH1A1 | |
| Bromide SCHEMBL15772385 | 0.63 | TSHR (0.37) | TDP1LMNATSHRALOX12ALDH1A1 | |
| Methylamine SCHEMBL9746311 | 0.63 | LMNA (0.37) | TDP1CYP2D6LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587440-A2 | Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same | NIPPON OIL COMPANY, LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |