Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409072 | 0.91 | MAPT (0.55) | ALDH1A1KDM4EMAPTGAARAB9A | |
| SCHEMBL9409100 | 0.85 | MAPT (0.59) | ALDH1A1KDM4EMAPTGAARAB9A | |
| SCHEMBL9409083 | 0.84 | MAPT (0.61) | ALDH1A1KDM4EMAPTGAARAB9A | |
| SCHEMBL9409108 | 0.83 | TSHR (0.51) | ALDH1A1KDM4EMAPTGAASIRT2 | |
| SCHEMBL9409337 | 0.83 | CSF1R (0.49) | ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9409164 | 0.83 | CDC25B (0.57) | ALDH1A1KDM4EMAPTSMN1; SMN2SIRT2 | |
| SCHEMBL9409163 | 0.82 | MAPT (0.50) | ALDH1A1HTTKDM4EMAPTRAB9A | |
| SCHEMBL9409146 | 0.82 | JAK2 (0.54) | ALDH1A1KDM4EMAPTGAASMN1; SMN2 | |
| SCHEMBL9409047 | 0.82 | MAPT (0.55) | KDM4EMAPTSIRT2ALOX15KMT2A | |
| SCHEMBL9409202 | 0.80 | MAPT (0.64) | ALDH1A1MAPTGAASIRT2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |