Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409050 | 0.91 | CSF1R (0.49) | CSF1RSIRT2MAPTALDH1A1KDM4E | |
| SCHEMBL9409100 | 0.88 | MAPT (0.59) | SIRT2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9409083 | 0.86 | MAPT (0.61) | SIRT2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9409108 | 0.85 | TSHR (0.51) | SIRT2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9409163 | 0.84 | MAPT (0.50) | CSF1RSIRT2MAPTALDH1A1KDM4E | |
| SCHEMBL9409047 | 0.84 | MAPT (0.55) | SIRT2MAPTKDM4EKMT2AALOX15 | |
| SCHEMBL9409146 | 0.84 | JAK2 (0.54) | SIRT2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9409103 | 0.83 | ALDH1A1 (0.50) | SIRT2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9409164 | 0.82 | CDC25B (0.57) | SIRT2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9409202 | 0.82 | MAPT (0.64) | SIRT2MAPTALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |