Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.52 |
| ▸ | DRD3 | P35462 | 12/20 | 0.52 |
| ▸ | DRD2 | P14416 | 12/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409396 | 0.89 | HTR2A (0.49) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| SCHEMBL9409417 | 0.89 | HRH3 (0.52) | HTR2ADRD3DRD2SLC6A5HDAC1 | |
| Hydrochloric Acid SCHEMBL9409457 | 0.88 | HTR2A (0.51) | HTR2ADRD3DRD2SLC6A5HDAC3 | |
| SCHEMBL9409500 | 0.86 | HDAC4 (0.48) | HTR2ADRD3DRD2HDAC4HDAC6 | |
| SCHEMBL9415854 | 0.86 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC3HDAC4 | |
| SCHEMBL9409367 | 0.86 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL9409523 | 0.85 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL9409352 | 0.85 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC3HDAC4 | |
| SCHEMBL9409599 | 0.83 | HTR2A (0.44) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9409359 | 0.83 | HTR2A (0.48) | HTR2ADRD3DRD2SLC6A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |