Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.49 |
| ▸ | DRD3 | P35462 | 10/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409500 | 0.92 | HDAC4 (0.48) | HTR2ADRD3DRD2LMNAKMT2A | |
| SCHEMBL9409599 | 0.90 | HTR2A (0.44) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| SCHEMBL9409398 | 0.89 | HTR2A (0.52) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| SCHEMBL9409417 | 0.87 | HRH3 (0.52) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| SCHEMBL9409541 | 0.86 | PDE4B (0.46) | HTR2ADRD3DRD2LMNAKMT2A | |
| SCHEMBL9409367 | 0.84 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| SCHEMBL9415854 | 0.84 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9409352 | 0.83 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9409523 | 0.83 | ALDH1A1 (0.46) | HTR2ADRD3DRD2HDAC1ALDH1A1 | |
| SCHEMBL4181896 | 0.79 | HDAC4 (0.57) | ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |